Mouse Dbi cDNA Clone(BC028874)

Name: Mouse Dbi cDNA Clone(BC028874)
SKU: CDFG022136
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFG022136

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Product Information

Gene Information

Cat. No.	CDFG022136
Product Type	cDNA clone
Gene Abbr	Dbi
Species	Mouse
ORF Size	500bp
Size	10 ug
Vector	pCMV6-Kan/Neo

Target Gene

DBI

Background

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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