Mouse Cox7a2l ORF clone (NM_001159529.1)

Name: Mouse Cox7a2l ORF clone (NM_001159529.1)
SKU: CDCR049940
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR049940

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Product Information

Gene Information

Cat. No.	CDCR049940
Description	Mus musculus cytochrome c oxidase subunit VIIa polypeptide 2-like (Cox7a2l), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Cox7a2l
Species	Mouse
ORF Size	405
Format	purified plasmid
Vector	pDONR

Target Gene

COX7A2L

Background

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]

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