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Mouse Acp2 cDNA Clone(BC023343)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG021738

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Gene Information

Cat. No. CDFG021738
Product Type cDNA clone
Gene Abbr Acp2
Species Mouse
ORF Size 2695bp
Size 10 ug
Vector pCMV6-Kan/Neo
Target Gene ACP2
Background The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]
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