Mouse ACP2 ORF clone(NM_007387.2)

Name: Mouse ACP2 ORF clone(NM_007387.2)
SKU: CDCH014772
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH014772

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Product Information

Gene Information

Cat. No.	CDCH014772
Product Type	ORF clone
Gene Abbr	ACP2
Species	Mouse
Host Cell	Bacterial
Source	Bacterial
ORF Size	4669bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mAcp2 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

ACP2

Background

The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]

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