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Human UBE2K cDNA Clone(NM_001111112.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFH020747

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Gene Information

Cat. No. CDFH020747
Product Type cDNA clone
Gene Abbr UBE2K
Species Human
Size 10 ug
Vector pCMV6-XL
Target Gene UBE2K
Background The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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