Human U2AF1 adenoviral particles

Name: Human U2AF1 adenoviral particles
SKU: AD17209Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD17209Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD17209Z
Description	Adenovirus with ORF of U2 small nuclear RNA auxiliary factor 1 (U2AF1), transcript variant a.
Gene	U2AF1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	U2AF1 U2 small nuclear RNA auxiliary factor 1 [ Homo sapiens ]
Gene Symbol	U2AF1
Synonyms	RN; FP793; U2AF35; U2AFBP; RNU2AF1
Gene Description	U2 small nuclear RNA auxiliary factor 1
Gene ID	7307
Uni Prot ID	Q01081
m RNA Refseq	NM_006758.2
Protein Refseq	NP_006749.1
Chromosome Location	21q22.3
Function	RNA binding; RS domain binding; nucleotide binding; protein binding; zinc ion binding;
Pathway	Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem; RNA Polymerase II Transcription Termination, organism-specific biosystem; Shigellosis, organism-specific biosystem; Spliceosome, organism-specific biosystem;
MIM	191317

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