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U2AF1

Official Full Name
U2 small nuclear RNA auxiliary factor 1
Organism
Homo sapiens
GeneID
7307
Background
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
RN; FP793; U2AF35; U2AFBP; RNU2AF1;

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