Human TGFBR2 HEK293 Cell Lysate

Name: Human TGFBR2 HEK293 Cell Lysate
SKU: CLOE-1478
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1478 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1478
Introduction	This cell lysate over-expresses the human TGFBR2 (NP_003233.4) (Met 1-Asp 159) fused with a polyhistidine tag and the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	TGFBR2
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens ]
Gene Symbol	TGFBR2
Synonyms	AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Gene Description	transforming growth factor, beta receptor II (70/80kDa)
GeneID	7048
Uni ProtID	D2JYI1
mRNA Refseq	NM_001024847.2
Protein Refseq	NP_001020018.1
Chromosome Location	3p22
Function	ATP binding; SMAD binding; glycosaminoglycan binding; metal ion binding; protein binding; contributes_to protein binding; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; transforming growth factor beta binding; transforming growth factor beta receptor activity, type II; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; type I transforming growth factor beta receptor binding; type I transforming growth factor beta receptor binding; type III transforming growth factor beta receptor binding;
Pathway	ALK1 signaling events, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem;
MIM	190182

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