Human TGFBR1 HEK293 Cell Lysate

Name: Human TGFBR1 HEK293 Cell Lysate
SKU: CLOE-1402
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1402 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1402
Introduction	This cell lysate over-expresses the human TGFBR1 (NP_004603.1) (Met 1-Glu 125) fused with a polyhistidine tag and the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	TGFBR1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	TGFBR1 transforming growth factor, beta receptor 1 [ Homo sapiens ]
Gene Symbol	TGFBR1
Synonyms	AAT5; ALK5; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
Gene Description	transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
GeneID	7046
Uni ProtID	P36897
mRNA Refseq	NM_004612.2
Protein Refseq	NP_004603.1
Chromosome Location	9q22
Function	ATP binding; I-SMAD binding; SMAD binding; SMAD binding; contributes_to growth factor binding; metal ion binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transforming growth factor beta binding; contributes_to transforming growth factor beta binding; transforming growth factor beta binding; transforming growth factor beta receptor activity, type I; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; contributes_to transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding;
Pathway	ALK1 signaling events, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem;
MIM	190181

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