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Human RAD54B Knockdown Cell Line-LN428 Glioma

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Cat.No.
CSC-RK0246
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
LN428 glioma
Ship
Dry ice
Gene Information
Official Symbol
RAD54B
Synonyms
RAD54B; RAD54 homolog B (S. cerevisiae); DNA repair and recombination protein RAD54B; RDH54;
Gene ID
MIM
UniProt ID
Q9Y620
Chromosome Location
8q22.1
Pathway
Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function
ATP binding; DNA helicase activity; DNA translocase activity; RNA helicase activity; hydrolase activity; nucleotide binding;

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