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RAD54B

Official Full Name
RAD54 homolog B (S. cerevisiae)
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Synonyms
RAD54B; RAD54 homolog B (S. cerevisiae); DNA repair and recombination protein RAD54B; RDH54

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