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Human RAD54B Knockdown Cell Line-HeLa

Human RAD54B Knockdown Cell Line-HeLa

Cat.No. :  CSC-RK0285

Host Cell:  HeLa Validation:  Real-Time RCR

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Cell Line Information

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Cat. No. CSC-RK0285
Background The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Gene RAD54B
Alias RAD54B, RDH54
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Morphology Epithelial
Stability Validated for at least 10 passages
Application

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size Form >1 × 10^6 cells / vial
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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