Human RAD54B Knockdown Cell Line-HeLa

Name: Human RAD54B Knockdown Cell Line-HeLa
SKU: CSC-RK0285
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0285

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0285
Background	The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Target Gene	RAD54B
Abbr	HeLa-HuRAD54B Knockdown
Alias	RAD54B, RDH54
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RAD54B RAD54 homolog B (S. cerevisiae) [ Homo sapiens ]
Gene Symbol	RAD54B
Synonyms	RAD54B; RAD54 homolog B (S. cerevisiae); DNA repair and recombination protein RAD54B; RDH54;
Gene ID	25788
Uni Prot ID	Q9Y620
m RNA Refseq	BC001965
Chromosome Location	8q22.1
Function	ATP binding; DNA helicase activity; DNA translocase activity; RNA helicase activity; hydrolase activity; nucleotide binding;
Pathway	Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
MIM	604289

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