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Human PRPS1L1 adenoviral particles

For research use only. Not intended for any clinical use.

Cat. No. :   AD12955Z

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. AD12955Z
Description Adenovirus with ORF of phosphoribosyl pyrophosphate synthetase 1-like 1 (PRPS1L1).
Gene PRPS1L1
Species Human
Titer Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.
Gene Name PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 [ Homo sapiens ]
Gene Symbol PRPS1L1
Synonyms PRPS1; PRPS3; PRPSL; PRS-III
Gene ID 221823
Uni Prot ID P21108
m RNA Refseq NM_175886.2
Protein Refseq NP_787082.1
Chromosome Location 7p21.1
Function ATP binding; kinase activity; magnesium ion binding; protein homodimerization activity; ribose phosphate diphosphokinase activity; ribose phosphate diphosphokinase activity;
Pathway 5-Phosphoribose 1-diphosphate biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; PRPP biosynthesis I, organism-specific biosystem; PRPP biosynthesis, ribose 5P => PRPP, organism-specific biosystem; PRPP biosynthesis, ribose 5P =>
MIM 611566
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