Panoply™ Human PRPS1L1 Knockdown Stable Cell Line

Name: Panoply™ Human PRPS1L1 Knockdown Stable Cell Line
SKU: CSC-DC012470
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012470

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012470
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PRPS1L1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 [ Homo sapiens ]
Gene Symbol	PRPS1L1
Synonyms	PRPS1; PRPS3; PRPSL; PRS-III
Gene ID	221823
Uni Prot ID	P21108
m RNA Refseq	NM_175886.2
Protein Refseq	NP_787082.1
Chromosome Location	7p21.1
Function	ATP binding; kinase activity; magnesium ion binding; protein homodimerization activity; ribose phosphate diphosphokinase activity; ribose phosphate diphosphokinase activity;
Pathway	5-Phosphoribose 1-diphosphate biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; PRPP biosynthesis I, organism-specific biosystem; PRPP biosynthesis, ribose 5P => PRPP, organism-specific biosystem; PRPP biosynthesis, ribose 5P =>
MIM	611566

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