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Human PRKDC Knockdown Cell Line - Glioma

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RK0240

Host Cell :   Glioma Validation :   Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No. CSC-RK0240
Description This cell line is engineered to stably express shRNA targeting human PRKDC.
Target Gene PRKDC
Host Cell Glioma
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Storage Liquid nitrogen
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens ]
Gene Symbol PRKDC
Synonyms HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs
Gene Description protein kinase, DNA-activated, catalytic polypeptide
Gene ID 5591
Uni Prot ID P78527
m RNA Refseq NM_006904.6
Protein Refseq NP_008835.5
Chromosome Location 8q11
Pathway BARD1 signaling events, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM 600899
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