Human PRKDC Knockdown Cell Line-HeLa

Name: Human PRKDC Knockdown Cell Line-HeLa
SKU: CSC-RK0267
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0267

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0267
Background	This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.
Target Gene	PRKDC
Abbr	HeLa-HuPRKDC Knockdown
Alias	PRKDC, DNA PKcs, DNAPK, DNPK1, p350, XRCC7, p460, HYRC, HYRC1, DNA-PKcs
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens ]
Gene Symbol	PRKDC
Synonyms	HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs
Gene Description	protein kinase, DNA-activated, catalytic polypeptide
Gene ID	5591
Uni Prot ID	P78527
m RNA Refseq	NM_006904.6
Protein Refseq	NP_008835.5
Chromosome Location	8q11
Pathway	BARD1 signaling events, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM	600899

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