Human PPM1D adenoviral particles

Name: Human PPM1D adenoviral particles
SKU: AD12705Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD12705Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD12705Z
Description	Adenovirus with ORF of protein phosphatase, Mg2+/Mn2+ dependent, 1D (PPM1D).
Gene	PPM1D
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D [ Homo sapiens ]
Gene Symbol	PPM1D
Synonyms	PPM1D; protein phosphatase, Mg2+/Mn2+ dependent, 1D; protein phosphatase 1D magnesium dependent, delta isoform; protein phosphatase 1D; PP2C DELTA; protein phosphatase 2C; delta isoform; wild type p53 induced phosphatase 1; Wip1; protein phosphatase Wip1; wild-type p53-induced phosphatase 1; protein phosphatase 2C delta isoform; protein phosphatase magnesium-dependent 1 delta; protein phosphatase 1D magnesium-dependent, delta isoform; WIP1; PP2C-DELTA;
GeneID	8493
Uni ProtID	O15297
mRNA Refseq	BC033893
Chromosome Location	17q23.3
Function	hydrolase activity; metal ion binding; protein binding; protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity;
Pathway	p53 pathway, organism-specific biosystem; p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem;
MIM	605100

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