Human NRG1(His) HEK293 Cell Lysate

Name: Human NRG1(His) HEK293 Cell Lysate
SKU: CLOE-1290
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1290 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1290
Introduction	This cell lysate over-expresses C-terminal polyhistidine tagged human NRG1 (NP_001153480.1) (Ser20-Lys238). Purification of target protein (s) from this cell lysate has been verified.
Target Gene	NRG1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	NRG1 neuregulin 1 [ Homo sapiens ]
Gene Symbol	NRG1
Synonyms	GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131
Gene Description	neuregulin 1
Gene ID	3084
Uni Prot ID	Q02297
m RNA Refseq	NM_013962.2
Protein Refseq	NP_039256.2
Chromosome Location	8p12
Function	ErbB-2 class receptor binding; ErbB-3 class receptor binding; ErbB-3 class receptor binding; cytokine activity; growth factor activity; growth factor activity; protein binding; protein tyrosine kinase activator activity; receptor binding; receptor tyrosine kinase binding; transcription cofactor activity; transmembrane receptor protein tyrosine kinase activator activity; transmembrane receptor protein tyrosine kinase activator activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downregulation of ERBB2:ERBB3 signaling, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem;
MIM	142445

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