Human NOD1 adenoviral particles

Name: Human NOD1 adenoviral particles
SKU: AD10877Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD10877Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD10877Z
Description	Adenovirus with ORF of nucleotide-binding oligomerization domain containing 1 (NOD1).
Gene	NOD1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	NOD1 nucleotide-binding oligomerization domain containing 1 [ Homo sapiens ]
Gene Symbol	NOD1
Synonyms	NOD1; nucleotide-binding oligomerization domain containing 1; CARD4, caspase recruitment domain family, member 4; nucleotide-binding oligomerization domain-containing protein 1; CLR7.1; NLR family; CARD domain containing 1; NLRC1; nucleotide binding oligomerization domain; leucine rich repeat and CARD domain containing 1; NLR family, CARD domain containing 1; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; CARD4;
Gene ID	10392
Uni Prot ID	Q9Y239
m RNA Refseq	BC040339
Chromosome Location	7p15-p14
Pathway	Activated TLR4 signalling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem;
MIM	605980

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