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Human KAT6A cDNA Clone(NM_001099412.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFH009566

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Product Information

Gene Information

Cat. No. CDFH009566
Product Type cDNA clone
Gene Abbr KAT6A
Species Human
Size 10 ug
Vector pCMV6-XL
Target Gene KAT6A
Background This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
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