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Human KAT6A ORF clone (NM_001099412.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL122611

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Product Information

Gene Information

Cat. No. CDCL122611
Description Homo sapiens K(lysine) acetyltransferase 6A (KAT6A), transcript variant 1, mRNA.
Product Type ORF clone
Gene Abbr KAT6A
Species Human
ORF Size 6015bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene KAT6A
Background This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
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