Human IRF7 adenoviral particles

Name: Human IRF7 adenoviral particles
SKU: AD08209Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD08209Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD08209Z
Description	Adenovirus with ORF of interferon regulatory factor 7 (IRF7), transcript variant a.
Gene	IRF7
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	IRF7 interferon regulatory factor 7 [ Homo sapiens ]
Gene Symbol	IRF7
Synonyms	IRF7A; IRF-7H
Gene Description	interferon regulatory factor 7
Gene ID	3665
Uni Prot ID	Q92985
m RNA Refseq	NM_004031.2
Protein Refseq	NP_004022.2
Chromosome Location	11p15.5
Function	DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II core promoter sequence-specific DNA binding; protein binding;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem;
MIM	605047

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