Human GABBR2 adenoviral particles

Name: Human GABBR2 adenoviral particles
SKU: AD06516Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD06516Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD06516Z
Description	Adenovirus with ORF of gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2).
Gene	GABBR2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 [ Homo sapiens ]
Gene Symbol	GABBR2
Synonyms	GABBR2; gamma-aminobutyric acid (GABA) B receptor, 2; G protein coupled receptor 51 , GPR51; gamma-aminobutyric acid type B receptor subunit 2; GABABR2; GPRC3B; HG20; gb2; GABA-BR2; GABA-B-R2; GABA-B receptor 2; GABA-B receptor, R2 subunit; G protein-coupled receptor 51; G-protein coupled receptor 51; gamma-aminobutyric acid B receptor 2; GPR51; HRIHFB2099; FLJ36928;
GeneID	9568
Uni ProtID	O75899
mRNA Refseq	BC035071
Chromosome Location	9q22.1-q22.3
Function	G-protein coupled GABA receptor activity; recep
Pathway	Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem;
MIM	607340

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