Human ERBB4(His) HEK293 Cell Lysate

Name: Human ERBB4(His) HEK293 Cell Lysate
SKU: CLOE-1477
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1477 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1477
Introduction	This cell lysate over-expresses C-terminal polyhistidine tagged human ERBB4 (NP_005226.1) (Met1-Arg649). Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ERBB4
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [ Homo sapiens ]
Gene Symbol	ERBB4
Synonyms	HER4; p180erbB4
Gene Description	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Gene ID	2066
Uni Prot ID	Q15303
m RNA Refseq	NM_001042599.1
Protein Refseq	NP_001036064.1
Chromosome Location	2q33.3-q34
Function	ATP binding; epidermal growth factor receptor binding; protein binding; protein homodimerization activity; protein tyrosine kinase activity; receptor signaling protein tyrosine kinase activity; transcription regulatory region DNA binding; transmembrane receptor protein tyrosine kinase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem;
MIM	600543

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