Human EIF4A2 adenoviral particles

Name: Human EIF4A2 adenoviral particles
SKU: AD05378Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD05378Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD05378Z
Description	Adenovirus with ORF of eukaryotic translation initiation factor 4A2 (EIF4A2).
Gene	EIF4A2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	EIF4A2 eukaryotic translation initiation factor 4A2 [ Homo sapiens ]
Gene Symbol	EIF4A2
Synonyms	DDX2B; EIF4A; EIF4F; BM-010; eIF4A-II; eIF-4A-II
Gene Description	eukaryotic translation initiation factor 4A, isoform 2
GeneID	1974
Uni ProtID	Q14240
mRNA Refseq	NM_001967.3
Protein Refseq	NP_001958.2
Chromosome Location	3q28
Function	ATP binding; ATP-dependent helicase activity; helicase activity; protein binding; translation initiation factor activity;
Pathway	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem;
MIM	601102

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