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Panoply™ Human EIF4A2 Knockdown Stable Cell Line

Cat.No.
CSC-DC004825
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
EIF4A2
Synonyms
DDX2B; EIF4A; EIF4F; BM-010; eIF4A-II; eIF-4A-II
Gene Description
eukaryotic translation initiation factor 4A, isoform 2
Gene ID
UniProt ID
Q14240
mRNA Refseq
Protein Refseq
Chromosome Location
3q28
Function
ATP binding; ATP-dependent helicase activity; helicase activity; protein binding; translation initiation factor activity;
Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem;
MIM

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