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Human DNAJC2 cDNA Clone(NM_014377.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFH005272

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Gene Information

Cat. No. CDFH005272
Product Type cDNA clone
Gene Abbr DNAJC2
Species Human
Size 10 ug
Vector pCMV6-XL
Target Gene DNAJC2
Background This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
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