Human DNAJC2 ORF clone (NM_001129887.1)

Name: Human DNAJC2 ORF clone (NM_001129887.1)
SKU: CDCR056488
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR056488

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Product Information

Gene Information

Cat. No.	CDCR056488
Description	Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 2 (DNAJC2), transcript variant 2, mRNA.
Product Type	ORF clone
Gene Abbr	DNAJC2
Species	Human
ORF Size	1707
Format	purified plasmid or bacterial stock
Vector	pDONR

Target Gene

DNAJC2

Background

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]

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