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HMGN3 Validated sgRNA vector

For research use only. Not intended for any clinical use.

Cat. No. :   SKO0525

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Cat. No. SKO0525
Description Creative Biogene develops and optimizes genome editing technology to produce stable genome edited mammalian cell lines serving a wide-range of R&D activities in areas of basic research, diagnostic and therapeutic development. Our premade SuperKO sgRNA vectors are tailor-made to target many different genes respectively. We have successfully constructed a series of knockout cell lines using those sgRNAs.
Gene Abbr HMGN3
Reporter mCherry
Promoter U6
Resistance Amp
Selection Ampicillin
Vector Type Lentiviral Expression
Vector Length 7677 bp
Target Gene HMGN3
Background The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]
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