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shRNA set against Rat MAP3K8 (NM_053847.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH337771

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Gene Information

Cat. No. SHH337771
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr MAP3K8
Gene Name Map3k8 mitogen-activated protein kinase kinase kinase 8 [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Map3k8 mitogen-activated protein kinase kinase kinase 8 [ Mus musculus ]
Gene Symbol Map3k8
Synonyms Cot; Est; Estf; Tpl2; Tpl-2; c-COT; Cot/Tpl2
Gene Description mitogen activated protein kinase kinase kinase 8
Gene ID 26410
Uni Prot ID Q07174
m RNA Refseq NM_007746.2
Protein Refseq NP_031772.1
Chromosome Location 18 A1; 18 0.0 cM
Function ATP binding; MAP kinase kinase kinase activity; kinase activity; magnesium ion binding; metal ion binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway Adaptive Immune System, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Insulin Signaling, organism-specific biosystem;
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