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shRNA set against Rat GJA1 (NM_012567.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH301290

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Gene Information

Cat. No. SHH301290
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr GJA1
Gene Name Gja1 gap junction protein, alpha 1 [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Gja1 gap junction protein, alpha 1 [ Mus musculus ]
Gene Symbol Gja1
Synonyms Cx43; Npm1; Cnx43; Gja-1; AU042049; AW546267; Cx43alpha1; connexin43
Gene Description gap junction membrane channel protein alpha 1
GeneID 14609
Uni ProtID P23242
mRNA Refseq NM_010288.3
Protein Refseq NP_034418.1
Chromosome Location 10 B4; 10 29.0 cM
Function PDZ domain binding; SH3 domain binding; beta-tubulin binding; gap junction channel activity; gap junction channel activity; protein binding; protein domain specific binding; receptor binding; signal transducer activity; transmembrane transporter activity;
Pathway Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Formation of annular gap junctions, organism-specific biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem;
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