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Panoply™ Human GJA1 Knockdown Stable Cell Line

Cat.No.
CSC-DC006277
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
GJA1
Synonyms
HSS; CX43; GJAL; ODDD; AVSD3; HLHS1; DFNB38
Gene Description
gap junction protein, alpha 1, 43kDa
Gene ID
UniProt ID
P17302
mRNA Refseq
Protein Refseq
Chromosome Location
6q21-q23.2
Function
PDZ domain binding; SH3 domain binding; gap junction channel activity; ion transmembrane transporter activity; protein binding; receptor binding; signal transducer activity;
Pathway
Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Formation of annular gap junctions, organism-specific biosystem; Gap junction, organism-specific biosystem;
MIM

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