Panoply™ Human GJA1 Knockdown Stable Cell Line

Name: Panoply™ Human GJA1 Knockdown Stable Cell Line
SKU: CSC-DC006277
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006277

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006277
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GJA1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GJA1 gap junction protein, alpha 1, 43kDa [ Homo sapiens ]
Gene Symbol	GJA1
Synonyms	HSS; CX43; GJAL; ODDD; AVSD3; HLHS1; DFNB38
Gene Description	gap junction protein, alpha 1, 43kDa
GeneID	2697
Uni ProtID	P17302
mRNA Refseq	NM_000165.3
Protein Refseq	NP_000156.1
Chromosome Location	6q21-q23.2
Function	PDZ domain binding; SH3 domain binding; gap junction channel activity; ion transmembrane transporter activity; protein binding; receptor binding; signal transducer activity;
Pathway	Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Formation of annular gap junctions, organism-specific biosystem; Gap junction, organism-specific biosystem;
MIM	121014

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