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shRNA set against Rat CDC27 (NM_001024793.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH259737

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Gene Information

Cat. No. SHH259737
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CDC27
Gene Name Cdc27 cell division cycle 27 [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Cdc27 cell division cycle 27 [ Mus musculus ]
Gene Symbol Cdc27
Synonyms APC3; AI452358; BC023187
Gene Description cell division cycle 27 homolog (S. cerevisiae)
GeneID 217232
Uni ProtID A2A6Q5
mRNA Refseq NM_145436.2
Protein Refseq NP_663411.2
Chromosome Location 11 E1; 11 63.0 cM
Function protein phosphatase binding;
Pathway APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem;
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