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shRNA set against Rat C1R (NM_001134555.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH250877

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Gene Information

Cat. No. SHH250877
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr C1R
Gene Name C1ra complement component 1, r subcomponent A [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name C1ra complement component 1, r subcomponent A [ Mus musculus ]
Gene Symbol C1r
Synonyms C1r; mC1rA; AI132558
Gene Description complement component 1, r subcomponent
Gene ID 50909
Uni Prot ID Q8CG16
m RNA Refseq NM_023143.3
Protein Refseq NP_075632.3
Chromosome Location 6 F2; 6
Function calcium ion binding; catalytic activity; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;
Pathway Classical antibody-mediated complement activation, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem;
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