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shRNA set against Rat BCKDHB (NM_019267.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH245830

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Gene Information

Cat. No. SHH245830
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr BCKDHB
Gene Name Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide [ Mus musculus ]
Gene Symbol Bckdhb
Gene Description branched chain ketoacid dehydrogenase E1, beta polypeptide
Gene ID 12040
Uni Prot ID Q6P3A8
m RNA Refseq NM_199195.1
Protein Refseq NP_954665.1
Chromosome Location 9 E2; 9
Function 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; alpha-ketoacid dehydrogenase activity; catalytic activity; oxidoreductase activity; protein complex binding;
Pathway Branched-chain amino acid catabolism, organism-specific biosystem; Leucine Catabolism, organism-specific biosystem; Leucine degradation, leucine => acetoacetate + acetyl-CoA, organism-specific biosystem; Leucine degradation, leucine => acetoacetate + acetyl-CoA, conserved biosystem; Metabolism, organism-specific biosystem;
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