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shRNA set against Rat ALKBH3 (NM_001014180.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH235242

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Gene Information

Cat. No. SHH235242
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ALKBH3
Gene Name Alkbh3 alkB, alkylation repair homolog 3 (E. coli) [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Alkbh3 alkB, alkylation repair homolog 3 (E. coli) [ Mus musculus ]
Gene Symbol Alkbh3
Synonyms Abh3; mABH3; 1700108H04Rik; 1810020C19Rik; RP23-375N21.4
Gene Description alkB, alkylation repair homolog 3 (E. coli)
Gene ID 69113
Uni Prot ID Q8K1E6
m RNA Refseq NM_026944.1
Protein Refseq NP_081220.1
Chromosome Location 2 E1; 2
Function DNA-N1-methyladenine dioxygenase activity; cytosine C-5 DNA demethylase activity; NOT endonuclease activity; NOT exonuclease activity; ferrous iron binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;
Pathway ABH3 mediated Reversal of Alkylation Damage, organism-specific biosystem; DNA Damage Reversal, organism-specific biosystem; DNA Repair, organism-specific biosystem; Reversal of Alkylation Damage By DNA Dioxygenases, organism-specific biosystem;
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