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shRNA set against Mouse SRD5A1 (NM_175283.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH417696

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Gene Information

Cat. No. SHH417696
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr SRD5A1
Gene Name Srd5a1 steroid 5 alpha-reductase 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Srd5a1 steroid 5 alpha-reductase 1 [ Mus musculus ]
Gene Symbol Srd5a1
Synonyms S5AR 1; Srd5a-1; 0610031P22Rik; 4930435F02Rik
Gene Description steroid 5 alpha-reductase 1
GeneID 78925
Uni ProtID Q68FF9
mRNA Refseq NM_175283.3
Protein Refseq NP_780492.2
Chromosome Location 13 C1; 13 39.0 cM
Function 3-oxo-5-alpha-steroid 4-dehydrogenase activity; 3-oxo-5-alpha-steroid 4-dehydrogenase activity; NADPH binding; amide binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-CH group of donors; progesterone 5-alpha-reductase activity;
Pathway Androgen biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Steroid hormone biosynthesis, organism-specific biosystem; Steroid hormone biosynthesis, conserved biosystem;
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