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shRNA set against Mouse SMAD4 (NM_008540.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH412988

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Gene Information

Cat. No. SHH412988
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr SMAD4
Gene Name Smad4 SMAD family member 4 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Smad4 SMAD family member 4 [ Mus musculus ]
Gene Symbol Smad4
Synonyms DPC4; Madh4; AW743858; D18Wsu70e
Gene Description MAD homolog 4 (Drosophila)
Gene ID 17128
Uni Prot ID P97471
m RNA Refseq NM_008540.2
Protein Refseq NP_032566.2
Chromosome Location 18 E2; 18 48.0 cM
Function DNA binding; DNA binding; I-SMAD binding; R-SMAD binding; SMAD binding; chromatin binding; collagen binding; core promoter proximal region sequence-specific DNA binding; identical protein binding; protein binding; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, common-partner cytoplasmic mediator activity;
Pathway Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Cell cycle signaling pathway, organism-specific biosystem;
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