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shRNA set against Mouse PAX8 (NM_011040.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH371188

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Gene Information

Cat. No. SHH371188
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PAX8
Gene Name Pax8 paired box gene 8 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Pax8 paired box gene 8 [ Mus musculus ]
Gene Symbol Pax8
Synonyms Pax-8
Gene Description paired box gene 8
Gene ID 18510
Uni Prot ID Q00288
m RNA Refseq NM_011040.3
Protein Refseq NP_035170.1
Chromosome Location 2 B; 2 13.5 cM
Function DNA binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transcription regulatory region DNA binding;
Pathway Id Signaling Pathway, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Thyroid cancer, organism-specific biosystem; Thyroid cancer, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
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