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shRNA set against Mouse OGG1 (NM_010957.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH357532

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Gene Information

Cat. No. SHH357532
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr OGG1
Gene Name Ogg1 8-oxoguanine DNA-glycosylase 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ogg1 8-oxoguanine DNA-glycosylase 1 [ Mus musculus ]
Gene Symbol Ogg1
Synonyms Mmh
Gene Description 8-oxoguanine DNA-glycosylase 1
GeneID 18294
Uni ProtID O08760
mRNA Refseq NM_010957.4
Protein Refseq NP_035087.3
Chromosome Location 6 E-F1; 6 48.0 cM
Function 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; DNA N-glycosylase activity; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; catalytic activity; damaged DNA binding; hydrolase activity; hydrolase activity, acting on glycosyl bonds; lyase activity; microtubule binding; oxidized base lesion DNA N-glycosylase activity; oxidized purine nucleobase lesion DNA N-glycosylase activity; oxidized purine nucleobase lesion DNA N-glycosylase activity; oxidized purine nucleobase lesion DNA N-glycosylase activity;
Pathway Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
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