shRNA set against Mouse MYOD1 (NM_010866.2)

Name: shRNA set against Mouse MYOD1 (NM_010866.2)
SKU: SHH348385
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH348385

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Product Information

Gene Information

Cat. No.	SHH348385
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	MYOD1
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Target Gene

Myod1

Background

Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and DNA-binding transcription factor binding activity. Contributes to DNA binding activity. Involved in several processes, including cellular response to estradiol stimulus; positive regulation of snRNA transcription by RNA polymerase II; and skeletal muscle cell differentiation. Acts upstream of or within several processes, including myotube differentiation; regulation of RNA metabolic process; and skeletal muscle fiber adaptation. Located in euchromatin; myofibril; and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; embryo mesenchyme; limb; limb bud; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital myopathy 17. Orthologous to human MYOD1 (myogenic differentiation 1). [provided by Alliance of Genome Resources, Feb 2025]

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