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shRNA set against Mouse HMGCS1 (NM_145942.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH313389

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Gene Information

Cat. No. SHH313389
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr HMGCS1
Gene Name Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 [ Mus musculus ]
Gene Symbol Hmgcs1
Synonyms B130032C06Rik
Gene Description 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Gene ID 208715
Uni Prot ID Q8JZK9
m RNA Refseq NM_145942.4
Protein Refseq NP_666054.2
Chromosome Location 13 66.0 cM; 13
Function catalytic activity; drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity; transferase activity;
Pathway Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Synthesis and degradation of ketone bodies, organism-specific biosystem;
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