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shRNA set against Mouse FGD3 (NM_015759.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH294317

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Gene Information

Cat. No. SHH294317
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr FGD3
Gene Name Fgd3 FYVE, RhoGEF and PH domain containing 3 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Fgd3 FYVE, RhoGEF and PH domain containing 3 [ Mus musculus ]
Gene Symbol Fgd3
Synonyms ZFYVE5; 5830461L01Rik
Gene Description FYVE, RhoGEF and PH domain containing 3
Gene ID 30938
Uni Prot ID Q3TNB8
m RNA Refseq NM_015759.2
Protein Refseq NP_056574.2
Chromosome Location 13 A5; 13 31.0 cM
Function Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; metal ion binding; phospholipid binding;
Pathway Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Rho GTPase cycle, organism-specific biosystem;
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