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shRNA set against Mouse CDK6 (NM_009873.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH260701

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Gene Information

Cat. No. SHH260701
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CDK6
Gene Name Cdk6 cyclin-dependent kinase 6 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Cdk6 cyclin-dependent kinase 6 [ Mus musculus ]
Gene Symbol CDK6
Synonyms Crk2; AI504062; 5830411I20
GeneID 12571
Uni ProtID Q0VBK8
mRNA Refseq NM_009873.2
Protein Refseq NP_034003.1
Chromosome Location 5 A2-A3; 5 1.0 cM
Function ATP binding; cyclin binding; cyclin-dependent protein kinase activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway B Cell Receptor Signaling Pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Cell cycle signaling pathway, organism-specific biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; Cyclin D associated events in G1, organism-specific biosystem; G1 Phase, organism-specific biosystem; G1 to S cell cycle control, organism-specific biosystem; Glioma, organism-specific biosystem; Glioma, conserved biosystem; Hepatitis B, organism-specific biosystem; Measles, organism-specific biosystem; Measles, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; Mitotic G1-G1/S phases, organism-specific biosystem; Non-small cell lung cancer, organism-specific biosystem; Non-small cell lung cancer, conserved biosystem; PI3K-Akt signaling pathway, organism-specific biosystem; PI3K-Akt signaling pathway, conserved biosystem; Pancreatic cancer, organism-specific biosystem; Pancreatic cancer, conserved biosystem; Pathways in cancer, organism-specific biosystem; Small cell lung cancer, organism-specific biosystem; Small cell lung cancer, conserved biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; Viral carcinogenesis, organism-specific biosystem; Viral carcinogenesis, conserved biosystem; p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem;
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