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shRNA set against Human THRB (NM_000461.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH427036

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Gene Information

Cat. No. SHH427036
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr THRB
Gene Name THRB thyroid hormone receptor, beta [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name THRB thyroid hormone receptor, beta [ Homo sapiens ]
Gene Symbol THRB
Synonyms GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA
Gene Description thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
GeneID 7068
Uni ProtID F1D8N7
mRNA Refseq NM_000461.4
Protein Refseq NP_000452.2
Chromosome Location 3p24.2
Function DNA binding; chromatin DNA binding; enzyme binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; transcription corepressor activity; zinc ion binding;
Pathway Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
MIM 190160
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  1. Rouleau S, Glouzon J P S, Brumwell A, et al. 3′ UTR G-quadruplexes regulate miRNA binding[J]. Rna, 2017, 23(8): 1172-1179.
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