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shRNA set against Human TDP1 (NM_018319.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH425288

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Gene Information

Cat. No. SHH425288
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TDP1
Gene Name TDP1 tyrosyl-DNA phosphodiesterase 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name TDP1 tyrosyl-DNA phosphodiesterase 1 [ Homo sapiens ]
Gene Symbol TDP1
Gene Description tyrosyl-DNA phosphodiesterase 1
GeneID 55775
Uni ProtID B3KN41
mRNA Refseq NM_001008744.1
Protein Refseq NP_001008744.1
Chromosome Location 14q32.11
Function 3-tyrosyl-DNA phosphodiesterase activity; double-stranded DNA binding; exonuclease activity; protein binding; single-stranded DNA binding;
Pathway DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Nonhomologous End-joining (NHEJ), organism-specific biosystem; Processing of DNA ends prior to end rejoining, organism-specific biosystem;
MIM 607198
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