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shRNA set against Human TCF7L2 (NM_030756.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH424876

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Gene Information

Cat. No. SHH424876
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TCF7L2
Gene Name TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) [ Homo sapiens ]
Gene Symbol TCF7L2
Synonyms TCF4; TCF-4
Gene ID 6934
Uni Prot ID Q9NQB0
m RNA Refseq NM_001146274.1
Protein Refseq NP_001139746.1
Chromosome Location 10q25.3
Function armadillo repeat domain binding; beta-catenin binding; beta-catenin binding; chromatin binding; gamma-catenin binding; nuclear hormone receptor binding; protein binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding;
Pathway Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem;
MIM 602228
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