shRNA set against Human NR1H4(NM_001206993.1)

Name: shRNA set against Human NR1H4(NM_001206993.1)
SKU: SHR019914
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHR019914

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Product Information

Gene Information

Cat. No.	SHR019914
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	NR1H4
Gene Name	NR1H4 nuclear receptor subfamily 1, group H, member 4 [ Homo sapiens ]
Species	Human
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs.
Promoter	H1
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg

Gene Name	NR1H4 nuclear receptor subfamily 1, group H, member 4 [ Homo sapiens ]
Gene Symbol	NR1H4
Synonyms	BAR; FXR; HRR1; HRR-1; RIP14
Gene Description	nuclear receptor subfamily 1, group H, member 4
GeneID	9971
Uni ProtID	F8VYG8
mRNA Refseq	NM_001206978.1
Protein Refseq	NP_001193907.1
Chromosome Location	12q23.1
Function	RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; bile acid binding; bile acid binding; double-stranded DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; ligand-dependent nuclear receptor binding; peptide binding; protein binding; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; transcription coactivator activity; transcription corepressor activity; zinc ion binding;
Pathway	Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem; RXR and RAR heterodimerization with other nuclear receptor, organism-specific biosystem;
MIM	603826

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