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shRNA set against Human NEDD4 (NM_006154.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH351064

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Gene Information

Cat. No. SHH351064
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NEDD4
Gene Name NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol NEDD4
Synonyms RPF1; NEDD4-1
Gene ID 4734
Uni Prot ID P46934
m RNA Refseq NM_006154.2
Protein Refseq NP_006145.2
Chromosome Location 15q
Function RNA polymerase binding; beta-2 adrenergic receptor binding; phosphoserine binding; phosphothreonine binding; proline-rich region binding; proline-rich region binding; protein binding; protein domain specific binding; sodium channel inhibitor activity; ubiquitin binding; ubiquitin-protein ligase activity;
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem;
MIM 602278
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