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shRNA set against Human LIG1 (NM_000234.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH330227

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Gene Information

Cat. No. SHH330227
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr LIG1
Gene Name LIG1 ligase I, DNA, ATP-dependent [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name LIG1 ligase I, DNA, ATP-dependent [ Homo sapiens ]
Gene Symbol LIG1
Gene Description ligase I, DNA, ATP-dependent
GeneID 3978
Uni ProtID P18858
mRNA Refseq NM_000234.1
Protein Refseq NP_000225.1
Chromosome Location 19q13.2-q13.3
Function ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase activity; metal ion binding;
Pathway Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem;
MIM 126391
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